Thiotepa for injection
WebDec 5, 2024 · Tepadina (thiotepa) for injection is an alkylating drug indicated to reduce the risk of graft rejection when used in conjunction with high-dose busulfan and cyclophosphamide as a preparative regimen for allogeneic hematopoietic progenitor (stem) cell transplantation (HSCT) for pediatric patients with class 3 beta-thalassemia; for … WebThiotepa can cause fetal harm when administered to a pregnant woman. Thiotepa given by the intraperitoneal (IP) route was tera-togenic in mice at doses ≥ 1 mg/kg (3.2 mg/m2), approximately 8-fold less than the maximum recommended human therapeutic dose (0.8 mg/kg, 27 mg/m 2), based on body-surface area. Thiotepa given by the IP route was ...
Thiotepa for injection
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WebJun 19, 2014 · THIOTEPA is given as an injection into a vein or directly into an organ or body space. THIOTEPA works by interfering with the growth of cancer cells. This slows their growth and eventually destroys them. The growth of normal cells in other parts of the body is affected by THIOTEPA as well. THIOTEPA is not addictive. Webof thiotepa in 20–60 mL of sterile water may be instilled after aspiration; in the USA, the licensed dose is 0.6–0.8 mg/kg, a dose similar to that suggested for injection directly into tumours. Thiotepa is available as 15 and 30 mg solu-tions for parenteral administration. 1.2.3 Trends in use Although thiotepa has largely been replaced
WebMar 28, 2024 · Thiotepa for Injection, USP is available in a single-dose vial containing: • 100 mg thiotepa. After reconstitution with 10 ml of water for injection, each ml contains 10 mg thiotepa. Thiotepa is a synthetic product with antitumor activity. The chemical name for thiotepa is Tris(1-aziridinyl)phosphine sulfide. WebJul 29, 2024 · LAKE ZURICH, Ill., July 29, 2024 – Fresenius Kabi announced today it has introduced Thiotepa for Injection, USP, in the United States. Thiotepa, a generic equivalent to Tepadina ® , is the newest addition to the company’s injectable oncology portfolio – the most comprehensive in the industry. Fresenius Kabi Thiotepa for Injection, USP is ...
WebProduct Name: Thiotepa for Injection CAS-No.: 52-24-4 1.2. Intended Use of the Product Thiotepa for injection is an alkylating drug indicated for treatment of adenocarcinoma of the breast or ovary, for controlling intracavitary effusions secondary to diffuse or localized neoplastic diseases of various serosal cavities, and for treatment of WebThiotepa for injection, USP is supplied as a non-pyrogenic, sterile lyophilized white powder for intravenous, intracavitary, or intravesical use after reconstitution and dilution. Thiotepa for injection, USP is available in a single-dose vial containing: · 15 mg thiotepa. After reconstitution with 1.5 ml of water for injection, each ml ...
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WebApr 2, 2024 · Thiotepa for Injection, USP is an ethylenimine-type compound. It is supplied as a non-pyrogenic, sterile Iyophilized powder for intravenous, intracavitary or intravesical … streaming station 19 saison 5 episode 3WebMay 14, 2024 · Thiotepa for Injection. Reason for the Shortage. West-Ward launched thiotepa in August 2015. West-Ward has product available. Amneal launched Tepadina in early 2024. Available Products. Tepadina injection, Amneal, 100 mg, vial, 1 count, NDC 70121-1631-01; Tepadina injection, Amneal, 15 mg, vial, 1 count, NDC 70121-1630-01; rowell\u0027s berry farmWebUSP Reference standards 11— USP Thiotepa RS . Completeness of solution 641— The contents of 1 container dissolved in Sterile Water for Injection or other diluent as directed in the labeling to obtain a solution containing 3.75 mg of thiotepa per mL yields a clear solution. Test and Standard solutions —Use the Assay solution and Standard ... rowell trucks indian trail ncWebAug 23, 2024 · Each of the YUMC-C1, YUMC-H2 and YUMC-P1 cell lines (4.5×10 6 cells/mouse) of Example 1 was cultured in test tubes and then was subcutaneously injected into the upper left flank regions of 6-week-old female BALB/c nude, NOD/Shi-scid, IL-2Rγ KOJic (NOG) mice. 15 days after injection of each of the cell lines, when the tumor volume … streaming station 19 saison 4 vfWebNov 14, 2024 · Thiotepa injection is used to lower risk of graft rejection when used with other medicines (eg, high-dose busulfan, cyclophosphamide) as a preparative regimen for stem cell transplantation in children with class 3 beta-thalassemia. It is also used to treat cancer of the breast, ovary, and urinary bladder. rowell\u0027s diseaseWebApr 25, 2024 · Thiotepa for Injection, USP is an ethylenimine-type compound. It is supplied as a non-pyrogenic, sterile Iyophilized powder for intravenous, intracavitary or intravesical administration, containing 15 mg of thiotepa. Thiotepa for injection is a synthetic product with antitumor activity. The chemical name for thiotepa is Aziridine, 1,1’1 ... rowell truckingWebThe store will not work correctly in the case when cookies are disabled. rowell tx